內專考題 血液腫瘤科

Bortezomib
http://www2.cch.org.tw/tumor/drug/drug23.htm
為proteosome inhibitor


藥物毒性

Fludarabine -- 免疫抑制
http://www.tccf.org.tw/old/medecine/nm_4.htm
Oxaliplatin -- 週邊神經病變
http://www.tccf.org.tw/old/medecine/nm_11.htm
Vinorelbine --白血球低下
http://www.tccf.org.tw/old/medecine/nm_5.htm

藥物機轉

Bevacizumab -- anti-VEGF
http://www.tccf.org.tw/old/medecine/nm_29.htm

Cetuximab --- anti- EGFRhttp://www.tccf.org.tw/old/medecine/nm_31.htm

摘自uptodate
prolonged PT: Factor VII deficiency, vitamin K deficiency, liver disease, warfarinprolonged aTTT: Deficiency of factors VIII, IX, or XI, von Willebrand disease, Lupus anticoagulant

Thrombotic Thrombocytopenic Purpura 的PT, APTT 大多是正常的

International prognosis scoring system (IPSS) in myelodysplastic syndrome
Bone marrow blasts , Karyotype, Cytopenias