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2011年4月13日 星期三

Lung cancer 整理

A New Target for Therapy in Squamous Cell Carcinoma of the Lung
http://cancerdiscovery.aacrjournals.org/content/1/1/23.abstract


FGFR1 amplification, EGFRvIII mutations, PIK3CA mutations, EGFR kinase domain mutations, DDR2 mutations


VEGF


Paclitaxel–Carboplatin Alone or with Bevacizumab for Non–Small-Cell Lung Cancerhttp://www.nejm.org/doi/full/10.1056/NEJMoa061884


ERCC1

DNA Repair by ERCC1 in Non–Small-Cell Lung Cancer and Cisplatin-Based Adjuvant Chemotherapy

http://www.nejm.org/doi/full/10.1056/NEJMoa060570





Micro-RNA

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

http://www.cell.com/cancer-cell/retrieve/pii/S153561080600033X


The microRNA world: small is mighty
http://lacim.uqam.ca/~chauve/Enseignement/BIF7001/H04/Devoir2/RNA-Nelson-TIBChem28.pdf





DNA methylation

DNA Methylation Markers and Early Recurrence in Stage I Lung Cancer

http://www.nejm.org/doi/full/10.1056/NEJMoa0706550#t=articleBackground


Gene Silencing in Cancer in Association with Promoter Hypermethylation

http://www.nejm.org/doi/full/10.1056/NEJMra023075



Low-dose CT


Overstating the Evidence for Lung Cancer Screening
The International Early Lung Cancer Action Program (I-ELCAP) Study
http://archinte.ama-assn.org/cgi/content/abstract/167/21/2289





Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer

http://jco.ascopubs.org/content/26/21/3543.abstract

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