Two Compartment Body Model
http://www.cop.ufl.edu/wp-content/uploads/2010/10/two-compartment-model.pdf

High protein binding
Midazolam, propofol, lorazepam, fentanyl  : 在protein loss or critical病人需減半使用



http://ccforum.com/content/13/6/1012

The propofol infusion syndrome: more puzzling evidence on a complex and poorly characterized disorder 

摘錄文中症狀如下
"arrythmia,
metabolic acidosis,
cardiac failure, and death 
rhabdomyolysis,
hyperkalemia,
lipidemia,
renal failure,
electrocardiographic abnormalities in the right precordial leads resembling the Brugada pattern"

http://www.medicine.virginia.edu/clinical/departments/medicine/divisions/digestive-health/nutrition-support-team/nutrition-articles/MikeArticle.pdf