Archive for 4月 2011
pulmonary edema 區分cardiogenic pulmonary edema or acute lung injury
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819058/?report=abstract
Determining the Etiology of Pulmonary Edema by the Edema Fluid-to-Plasma Protein Ratio
使用 suction catheter 到distal airway, 取得edema fluid
再測 edema fluid 和plasma 的total protein
EF/PL ratio > 0.84 favor acute lung injury
EF/PL ratio > = 0.65 higher mortality
CXR 胸部x光判讀 Pneumoconiosis
Coal miner
Pneumoconiosis (磁磚工人)
Silicosis (silica): risk for TB, lung cancer, COPD, connective tissure disease
coal: risk for COPD, chronic bronchitis
Asbesto: risk for malignant mesothelioma, lung cancer
Symptoms: dyspnea, weight loss, weakness, cough (維基百科)
Pneumoconiosis (磁磚工人)
Silicosis (silica): risk for TB, lung cancer, COPD, connective tissure disease
coal: risk for COPD, chronic bronchitis
Asbesto: risk for malignant mesothelioma, lung cancer
Silicoproteinosis: high-resolution CT findings in 13 patients.
http://www.ajronline.org/cgi/content/abstract/189/6/1402
acute silicosis: 像 pulmonary alveolar proteinosisSymptoms: dyspnea, weight loss, weakness, cough (維基百科)
Lung cancer 整理
A New Target for Therapy in Squamous Cell Carcinoma of the Lung
http://cancerdiscovery.aacrjournals.org/content/1/1/23.abstract
FGFR1 amplification, EGFRvIII mutations, PIK3CA mutations, EGFR kinase domain mutations, DDR2 mutations
VEGF
Paclitaxel–Carboplatin Alone or with Bevacizumab for Non–Small-Cell Lung Cancerhttp://www.nejm.org/doi/full/10.1056/NEJMoa061884
Micro-RNA
The microRNA world: small is mighty
http://lacim.uqam.ca/~chauve/Enseignement/BIF7001/H04/Devoir2/RNA-Nelson-TIBChem28.pdf
Low-dose CT
Overstating the Evidence for Lung Cancer Screening
The International Early Lung Cancer Action Program (I-ELCAP) Study
http://archinte.ama-assn.org/cgi/content/abstract/167/21/2289
http://cancerdiscovery.aacrjournals.org/content/1/1/23.abstract
FGFR1 amplification, EGFRvIII mutations, PIK3CA mutations, EGFR kinase domain mutations, DDR2 mutations
VEGF
Paclitaxel–Carboplatin Alone or with Bevacizumab for Non–Small-Cell Lung Cancerhttp://www.nejm.org/doi/full/10.1056/NEJMoa061884
ERCC1
DNA Repair by ERCC1 in Non–Small-Cell Lung Cancer and Cisplatin-Based Adjuvant Chemotherapy
http://www.nejm.org/doi/full/10.1056/NEJMoa060570
Micro-RNA
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
http://www.cell.com/cancer-cell/retrieve/pii/S153561080600033XThe microRNA world: small is mighty
http://lacim.uqam.ca/~chauve/Enseignement/BIF7001/H04/Devoir2/RNA-Nelson-TIBChem28.pdf
DNA methylation
DNA Methylation Markers and Early Recurrence in Stage I Lung Cancer
http://www.nejm.org/doi/full/10.1056/NEJMoa0706550#t=articleBackgroundGene Silencing in Cancer in Association with Promoter Hypermethylation
http://www.nejm.org/doi/full/10.1056/NEJMra023075Low-dose CT
Overstating the Evidence for Lung Cancer Screening
The International Early Lung Cancer Action Program (I-ELCAP) Study
http://archinte.ama-assn.org/cgi/content/abstract/167/21/2289
Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer
http://jco.ascopubs.org/content/26/21/3543.abstractCXR 胸部x光判讀 Diffuse panbronchiolitis
Diffuse small nodular shadows
male, nonsmoker, chronic sinusitis
use macrolide to decrease IL-8
瀰漫性泛細支氣管炎
http://www.tafm.org.tw/Data/011/382/160306.pdfDPB: HLA B54
Goodpasture's syndrome: HLA DRB1*1501, HLA-DR15, HLA-DR4, HLA DR2,
myasthenia gravis: HLA-DR3, B8, A1