Posted by : Chih-Hao Chang 2009年9月12日 星期六

Bortezomib
http://www2.cch.org.tw/tumor/drug/drug23.htm

為proteosome inhibitor


藥物毒性

Fludarabine -- 免疫抑制
http://www.tccf.org.tw/old/medecine/nm_4.htm

Oxaliplatin
-- 週邊神經病變
http://www.tccf.org.tw/old/medecine/nm_11.htm

Vinorelbine --白血球低下
http://www.tccf.org.tw/old/medecine/nm_5.htm


藥物機轉

Bevacizumab -- anti-VEGF
http://www.tccf.org.tw/old/medecine/nm_29.htm


Cetuximab --- anti- EGFRhttp://www.tccf.org.tw/old/medecine/nm_31.htm

摘自uptodate
prolonged PT:
Factor VII deficiency, vitamin K deficiency, liver disease, warfarin
prolonged aTTT: Deficiency of factors VIII, IX, or XI, von Willebrand disease, Lupus anticoagulant

Thrombotic Thrombocytopenic Purpura 的PT, APTT 大多是正常的




International prognosis scoring system (IPSS) in myelodysplastic syndrome

Bone marrow blasts , Karyotype, Cytopenias

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